The duomo of Viterbo is one of the most historically significant in Italy. It is located near the Palazzo dei Papi, and eight popes were crowned in this church. Its origins trace back to a pagan temple dedicated to Hercules, on the remains of which a church was built in honor of Saint Lawrence.

The current structure was built in 1200, and the Renaissance façade was added in 1570. The church houses the tomb of Pope John XXI, who died in 1277 in a building adjacent to the church after the roof of his room collapsed while he was sleeping.

The church’s floor is a beautiful mosaic. A unique feature of the cathedral is its two apses: a Baroque apse, adorned with decorations, was damaged during World War II and is located behind the current apse.